7/27/2023 0 Comments Highdesign for mac![]() We added a few important features and mostly worked hard on improving the performance and enhancing the existing feature set. Although the extra work needed to develop and test HighDesign on both the ARM and the x86 architectures added some more weeks to the final R6 release, we’re very pleased with the work done for this update. With the announcement of the new Macs on November 10th, we at ILEXSOFT decided to make supporting the new platform a priority. CAD and architecture design require big computational power, and these new Apple Silicon chips, along with the latest Intel and AMD chips, are a good platform. This is a particularly good news for the Mac and for the architecture, engineering and construction professionals, who can now consider powerful and reasonably accessible new computers for the heavy work of drafting and design. Having worked every day on a new M1 Mac for some months, we can say that the press hype is well justified: the machine is really fast, even compared to a same level i7 Mac. ![]() That is case with the new Apple Silicon M1 chip. Once in a while a technological innovation changes the game in the software industry. aucl on Happy New Year (and Next Release).Ilexsoft on Happy New Year (and Next Release).Ilexsoft on HighDesign R6 with Apple Silicon Support.aucl on HighDesign R6 with Apple Silicon Support.HighDesign R6.1 Adds New Graphics Features, macOS Monterey Support.Tutorial: Adding Hatches and Textures to the Project.
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![]() In the interests of full transparency, we ask you to read our legal disclaimer, which sets out the legal basis of your use of this web site. Minitab, so you can be confident that you're not being led astray by using our Output produced by a number of established statistics packages, including SPSS and The output of the calculators and tools featured on this web site has been audited for accuracy against the Which allow you to derive p-values from Z, t, chi-square and Pearson ( r) and descriptive statistics - averages, variance, a standard deviation calculator, Which deals mainly with hypothesis testing p-value calculators, The web site has three main sections: statistical calculators, You should find them much less cumbersome - and definitely less expensive! - than With ease of use and clarity of presentation in mind. ![]() All the calculators and tools featured here have been designed Theme_bw () + theme(plot.title = element_text(lineheight=.8, face="bold"), legend.This web site offers free resources for students and researchers working with statistics Geom_abline (intercept=intercept, slope=mod$coefficients, color="#4795c3", linetype=2) + P + geom_point (shape=20, aes(colour="#dddddd")) + Sdp = mapply(rotate, xsd, standard_dev*ysd, -angle, -intercept) Xpp = mapply(rotate, xp, yp, -angle, -intercept) # Transform back the data, and two curves for the + and - standard dev Ysd = sapply(xsd, sdWindow, window, xp, yp) ScatterPlot = pos-window/2 & x <= pos+window/2) A limit on expression level and fold change remains our best option when working without replicates. Also, the standard deviation threshold alone would probably not be an excellent criteria to identify interesting genes as it would tend to select many lowly expressed ones. It would in fact be the same if the rotation angle was exactly pi/4. This yields:Ī keen observer will note that this is almost the same as computing a windowed standard deviation curve of the A values of a MA plot along the M axis. We can then compute a windowed standard deviation on the y’ values along the x’ axis and transform back these values as two curves using a rotation of -Theta. This is simply done by converting each coordinate (x,y) using a rotation matrix: Then, rotate the distribution by the angle corresponding to that slope, or atan(m), but clockwise so that Theta=-atan(m). In my case, I obtained 0.986, not bad at all. First, fit a linear model on the distribution to obtain the slope (m) of the model, which should incidentally be close to 1 if data is correctly normalized. Eventually, we obtained replicates for this projects and I then performed a full blown differential expression analysis using DESeq2 in which I used the adjusted p-value to color significant genes (p-adj < 0.001):įast forward a few weeks later and the answer suddenly appeared out of nowhere in the form of simple geometry and I ended up testing the following. That makes perfect sense although after many minutes of search, no answer was in sight. My colleague was quick to point out that this was less than satisfying and that (s)he was expecting the standard deviation to vary along the diagonal. This turns out to be equivalent to computing the standard deviation of the residual of a linear model fitted on this distribution. As a first draft, I quickly obliged by calculating the fold change distribution, computing standard deviation and drawing lines on either side of the diagonal to obtain: I was recently asked by a colleague to provide visualization of differential gene expression computed using RPKM values (two samples, no replicates) and highlight genes that were outside the distribution by 2 standard deviations or more. 7/27/2023 0 Comments Treating severe insomnia![]() ![]() For a lot of people whose work schedules have changed, there’s no getting outside first thing in the morning to physically get to an office or place of work. ![]() Get natural light. “Something that’s happened a lot since 2020 is that because a lot of people are now working from home, there is no daily routine,” Attarian says.This means going to bed and waking up around the same time, whether it’s Wednesday or Sunday. Here are some good sleep hygiene practices Dr. Attarian, MD, a sleep medicine specialist at Northwestern Medicine in Chicago, says he always starts by analyzing a person’s sleep and wake habits. Here are some of the treatment options your doctor or a sleep specialist might recommend if you have insomnia.įor a mild case that’s been a problem only for a few days or weeks, doctors will likely recommend a few lifestyle changes to promote better sleep. Lifestyle changes, therapies, and other treatments do exist to retrain your mind and body to get the sleep you need to stay not only happy but healthy, too. What’s more, those periods of short-term insomnia that last just a few days or a week ( acute insomnia), can turn into longer-term insomnia, which is known as chronic insomnia, meaning your sleep troubles last beyond the initial stressor.īut you don't have to suffer through short- or long-term insomnia, and you shouldn't. There are many reasons why you might be struggling to fall asleep or stay asleep through the night, including stressful life events (such as getting fired from a job) and health issues. Experts estimate that between 1 in 10 and 1 in 3 people suffer from some degree of insomnia, meaning they have trouble falling asleep, staying asleep, or wake up earlier than they intend to in the morning (or a combination of the above). You feel like you’re cursed - but you’re not alone. There are no FDA-approved drugs to treat insomnia in children, although some evidence supports use of melatonin for sleep-onset problems in children with neurodevelopmental disorders.You lie awake at night staring at the ceiling. Side effects (confusion and falls) and habit-forming potential should be considered. Medications should be chosen so that the timing of their effect matches the time of night affected by the insomnia (trouble falling asleep, trouble staying asleep, or early morning awakening). Some drugs without FDA approval for treatment of insomnia are also commonly used, including trazadone, quetiapine, gabapentin, melatonin, and over-the-counter sleep aids. US Food and Drug Administration (FDA)–approved drugs for insomnia include nonbenzodiazepine hypnotics (zolpidem, zaleplon, eszopiclone), benzodiazepines (triazolam, temazepam), selective histamine antagonists (doxepin), melatonin receptor agonists (ramelteon), and hypocretin/orexin receptor antagonists (suvorexant, lemborexant). If chronic insomnia does not improve with CBTI, adults may benefit from medication. CBTI can be done in person or via telehealth, web-based, or app-based tools. CBTI also gives behavioral recommendations, including establishing a wake-up time, restricting time in bed, reserving the bed for sleep and sex, avoiding naps, and recommending against caffeine, alcohol, use of electronic screens, and exercise close to bedtime. Patients with severe acute insomnia may also benefit from short-term use of medications to decrease the physical and psychological effects of sleepiness and to reduce the likelihood of developing dysfunctional behavioral responses to insomnia.įor chronic insomnia, first-line treatment is cognitive behavior therapy for insomnia (CBTI), which aims to reduce fear and anxiety about sleeping and provide bedtime relaxation strategies. Shared Decision Making and Communicationįor short-term insomnia, discussion with a clinician about the stressor causing sleep difficulty may be helpful.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography. 7/27/2023 0 Comments Best free piano tuning software![]() Gazelle has a team that they hire just for the purpose of importing data. I even had my files in a simple notepad database and all my data was imported successfully! However, when it comes down to hitting that start trial button they freeze up wondering how in the world they would get 20 years of customer data in to an online system?īut whether it's 20 years of paper documents or electronic data in any format, Gazelle has you covered. I have spoken to many piano technicians who would love to use Gazelle and even praise it for all of its innovations. But they were all lacking in updates, features and help! Gazelle is constantly getting updates and new features added to improve our businesses at a very reasonable price! If I sign up for Gazelle, how will they deal with all my existing customer data? I have used other customer management systems that were supposed to be designed for piano technicians. If our customers have to jump through hoops to have their piano tuned they will go elsewhere. Not only does Gazelle help you save time with your day to day work it gives your clients an easy way to do business with you as well.
7/27/2023 0 Comments Samsung online doctor visitsPreviously Japanese doctors were only allowed to treat recurring patients remotely, and for a limited number of diseases. The reforms could also help Japan grapple with both a skyrocketing healthcare burden and few doctors in rural areas. The changes mark a potential shake-up in one of the world’s biggest medical markets, which has lagged countries like Australia, China, and the United States in telemedicine. REUTERS/Issei KatoĪs coronavirus cases spiked in April, Japan temporarily eased restrictions on remote medical care, allowing doctors to conduct first-time visits online or by telephone and expanding the number of illnesses that can be treated remotely. What do you think? Is this something you’ll use? Let us know down below in the comments or carry the discussion over to our Twitter or Facebook.Medical doctor Makoto Kitada demonstrates a telemedicine application service called 'CLINICS', developed by Japanese medical start-up Medley Inc., in Tokyo, Japan, July 8, 2020. It’ll only do this if you specifically ask for it.Įditor’s Note: Alex John is an editor over at TechAcrobat. The application won’t automatically save reports as PDF files in order to ensure privacy and avoiding reports getting into the wrong hands. Keep in mind that this option is not free you’ll be charged in case you scheduled an online consultancy (you also have the option to register your insurance provider in specified countries). Press on ‘ See Online Doctor’ in case you want to talk with a doctor about your condition. That’s not all: there is also an option to consult a doctor after producing the report. Tick the checkbox stating that you have read and agreed, and then press the ‘ Continue’ button. Now, the app will display a message saying that Samsung Health is not a substitute for professional medical advice (as previously explained). A new screen will appear with a ‘ Check Symptoms’ button. First, open the application and go to the ‘ Experts’ tab found in the menu at the bottom of the page. It’s easy to research a symptom using the Samsung Health App. Check Your Symptoms Using Samsung Health Symptom Checker Step 1: Starting In brief, the Samsung Health Symptom Checker is helpful as a starting point as it does a good job in clarifying the roots of any unusual symptoms. ![]() It is always better, and safer, to visit a doctor’s office for a proper diagnosing that will leave you with a peace of mind. ![]() You should never completely rely on the Symptom Checker feature of the Samsung Health app (or any other application) only use them for reference purposes. ![]() It is important to keep in mind that this feature might only replace a visit to a doctor in some minor cases. It is a great app for monitoring daily workouts and nutrition plans, but what makes it stand out is the Samsung Health Symptom Checker feature that can help you diagnose newly developed symptoms while sitting at home. This application helps you build a personalized profile that can help you organize your health habits and enhance your overall wellbeing. When it comes to being at the top of your body’s health and wellbeing, Samsung’s Health App proves to be of great benefit. 7/26/2023 0 Comments Adventure quest 3d 2022Interesting experiments, if nothing else. They’re not much, usually a corridor that’s topped with a puzzle or a small boss. Mini-dungeons are something that I discovered about Guild Wars 2, thanks to dailies. Oh! And I picked up my free Massively OP cloak that I had totally forgotten I unlocked several years back. ![]() So I focused on popping my head into the first zone, doing a couple of Ranger quests to get tokens for that class, and hung out with the weird band at the inn. There were so many quest givers and things to do and places to see that I didn’t know what to do first. There is insta-travel between regions, though.īy the time I got to the main town, I felt in over my head. But for the first night, I worked on getting my game legs with combat, gearing up, and getting to know a questing system where there is no mini-map or bigger map. What seems to distinguish itself is the generally wacky humor (I am a fan of the drackens - the dragon-chicken hybrids) and the ability to collect and swap between classes. It’s a very straight-forward - and slick! - MMO with tab-target combat, loot, stats, etc. If you’ve played any MMO, ever, then AQ3D is not going to trip you up. ![]() MJ over at MOP is a huge evangelist for this game and keeps saying how it’s incredibly underrated, so I must give it more than a passing time of day, I suppose. Best case, I find something that’s surprisingly fun and sticks.įirst up? AdventureQuest 3D. I have a list of MMOs I either haven’t tried, haven’t played much, or haven’t visited in a while, so until the funk is over, I’ll be visiting one of these on a week-by-week basis. Feeling a bit in a routine funk as of late, I pulled on the emergency cord by my desk to activate a good old-fashioned MMO tour. 7/26/2023 0 Comments Block city wars cheats ipad![]() ![]() Set the world spawn location to the player's current position, or optional specified coordinates if entered.Produces a seed code so you can recreate your world later.Caret offsets are based on the direction the player's head is facing along left, upward, and forward axes, so ^5 ^ ^-5 would be 5 blocks left, 0 blocks upward (same height), and 5 blocks backward. Tilde offsets are based on the world coordinates, so ~5 ~ ~-5 would be +5 blocks on x (east), 0 blocks on y (same height), and -5 blocks on z (north). You can also use tilde (~) or caret (^) notation with a number to express relative coordinates offset from your current position, with the notation by itself representing ~0 or ^0 ie no offset. Minecraft world and environment cheats and commandsįor coordinates, these are expressed as x, y, z, where x is the distance east (+) or west (-) of the origin point, z is the distance south (+) or north (-) of the origin point, and y is the height from -64 to 320, where 62 is sea level. Whether you're on Bedrock or Java Edition, speed up entering Minecraft cheats and commands by using these shortcuts to quickly to select specific targets for your command: Put the word levels on the end to add experience levels instead ![]() Adds the stated amount of experience points to the specified player.Apply the enchantment to the specified player's selected item, at an optional level.Clear all effects, or optionally just the specified effect, from the player or entity.Applies the effect to the specified player or entity, for an option duration in seconds.Teleport yourself (or specified player) to the coordinates entered.(Image credit: Mojang) Minecraft player cheats and commands 7/26/2023 0 Comments Amazing grace lotion 32 ozI have no idea why, but whenever I smell this lotion, I just think of traveling to Europe. ![]() I know that this is going to sound hella weird, but this lotion, to me, smells like Europe. It’s a very delightful, fresh, soft and clean scent that reminds me a little of a Nivea cream, but it’s much more subtle. ![]() It smells so nice, to the point that I don’t feel the need to wear perfume. Not only that, but the smell lingers on your skin forever, literally, it lasts until you wash it off in the shower. I have to say, that this is the BEST smelling lotion that I have ever used. “Chock full of luscious moisturizing properties including shea butter, macadamia nut, and olive oils for a unique blend of antioxidants and vitamins E and C, this enchanting, creamy emulsion creates soft, touchable, and subtly scented skin.” I’ve never been disappointed by anything from Philosophy and the Amazing Grace firming emulsion is no different. We may cancel or change this offer or cancel your order without notice due to insufficient supply, your noncompliance with offer terms, lack of bank authorization, system error, unforeseen problems, or for any other reason. NOT COMBINABLE WITH any other promotion, sale, discount, outlet item, or discounted value or gift set.Īpplicable purchase amount does not include items not in stock at time of purchase, items not designated for the offer, pending purchases, or purchases made before or after the offer period, or any offer fees or costs, such as cost of shipping, handling, and sales tax. Customer may choose only one gift to redeem. ![]() Purchases from our offline store do not qualify. Offer: Available to residents of the U.S. Gift includes: purity made simple cleanser 1oz, purity made simple pore extractor mask. ![]() Enjoy a 4-piece gift with your purchase of $55 or more on .Īdd purchase to cart and select gift at checkout to redeem. Microsoft Office comes with several tools, as it follows: Excel, Outlook, PowerPoint, Word, Access, InfoPath, OneNote, Project, SharePoint Designer and Visio. Experimenting with the suite is necessary to ensure smooth operation in the future. ![]() However, upon further analysis, one can find components or functions with every mouse click, and this might seem confusing if users do not know exactly the tool they require. Complex features and multiple tools to use ![]() At the first glance, due to the well-known ribbon interface, the app might seem familiar. Those who have not used an office suite before, be it Microsoft Office, OpenOffice or any other similar software, need to take the time to adjust to the interface. Also, copying all files usually takes a while, even in the case of fast computers, since there are a lot of files that need to be transferred on the hard disks. Installing Microsoft Office might seem a little tricky, since there are a lot of tools bundled into the installation kit, so computer knowledge can come in handy when trying to deploy a fresh copy of the software. Text editor, spreadsheet tool, email client, presentation maker, and note taker in one suite ![]() Updates are frequently rolled out to continuously improve the Office suite, so it currently comes with a very attractive interface that keeps features a bit more organized, so that users can now benefit easier from its innovative functions. Office is one of the best products ever released by Microsoft and it can even be considered as a must-have for millions of users out there. 7/26/2023 0 Comments Porcine gelatin vs bovine gelatin![]() ![]() ![]() When later describing the event, the girl stated that it was “kind of like what happens when I eat Jell-O®.” Subsequent testing found that the only component of the vaccine to which this girl was allergic was gelatin. Her symptoms resolved after treatment with epinephrine. In 1993, Kelso and co-workers reported the case of a 17-year-old girl in California who developed a severe allergic reaction (hives, low blood pressure, runny nose and lightheadedness) within five minutes of receiving an MMR (measles, mumps and rubella) vaccine. Quantity per dose: 8.9-12.5 mg Yellow fever (YF-Vax®) Quantity per dose: Gelatin capsule Varicella (Varivax®) Note: The gelatin product used in this vaccine is of bovine origin. Quantity per dose: 11 mg Rabies (Rabavert®) Quantity per dose: 14.5 mg Measles, mumps, rubella, varicella (ProQuad®) Quantity per dose: 2 mg Measles, mumps, rubella (MMR II®) Gelatin content of vaccines licensed in the United States, 2019 Live, attenuated influenza (Flumist®) An exception is one of the rabies vaccines, called Rabavert, which uses gelatin that is of bovine origin. Gelatin is a protein formed by boiling skin or connective tissue. Gelatin contained in most vaccines is porcine in origin. Gelatin is contained in some vaccines to protect vaccine viruses from adverse conditions such as freeze-drying or heat, particularly during transport and delivery (see table below). |